Weill Cornell Medical College
The effect of NADH on DNA repair was investigated on PC12 cells, damaged by doxorubicin. PC12 cells ware incubated in medium without and with NADH before and after exposure to the DNA damaging agent doxorubicin. The changes of the cell proliferation genes (c-myc, c-erbB-2), the apoptosis inhibition gene bcl-2 and p53 (tumor suppressor gene), cell apoptosis gene (c-fos) and the proliferating cell...read more